Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure

The effectiveness of cell-based therapies to treat liver failure is often limited by the diseased liver environment. Here, we provide preclinical proof of concept for hepatocyte transplantation into lymph nodes as a cure for liver failure in a large-animal model with hereditary tyrosinemia type 1 (H...

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Detalles Bibliográficos
Autores principales: Nicolas, Clara T., Kaiser, Robert A., Hickey, Raymond D., Allen, Kari L., Du, Zeji, VanLith, Caitlin J., Guthman, Rebekah M., Amiot, Bruce, Suksanpaisan, Lukkana, Han, Bing, Francipane, Maria Giovanna, Cheikhi, Amin, Jiang, Huailei, Bansal, Aditya, Pandey, Mukesh K., Garg, Ishan, Lowe, Val, Bhagwate, Aditya, O’Brien, Daniel, Kocher, Jean-Pierre A., DeGrado, Timothy R., Nyberg, Scott L., Lagasse, Eric, Lillegard, Joseph B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452193/
https://www.ncbi.nlm.nih.gov/pubmed/32913881
http://dx.doi.org/10.1016/j.omtm.2020.07.009

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