Cargando…

Autoinhibition of TRPV6 Channel and Regulation by PIP2

Transient receptor potential vanilloid 6 (TRPV6), a calcium-selective channel possessing six transmembrane domains (S1-S6) and intracellular N and C termini, plays crucial roles in calcium absorption in epithelia and bone and is involved in human diseases including vitamin-D deficiency, osteoporosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Ruiqi, Liu, Xiong, Zhang, Rui, Hofmann, Laura, Zheng, Wang, Amin, Md Ruhul, Wang, Lingyun, Hu, Qiaolin, Peng, Ji-Bin, Michalak, Marek, Flockerzi, Veit, Ali, Declan W., Chen, Xing-Zhen, Tang, Jingfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452202/ https://www.ncbi.nlm.nih.gov/pubmed/32829285 http://dx.doi.org/10.1016/j.isci.2020.101444

Ejemplares similares

Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2
por: Zheng, Wang, et al.
Publicado: (2018)

Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion
por: Cai, Ruiqi, et al.
Publicado: (2021)

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
por: Zheng, Wang, et al.
Publicado: (2018)

Author Correction: Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
por: Zheng, Wang, et al.
Publicado: (2019)

Structure of autoinhibited Akt1 reveals mechanism of PIP(3)-mediated activation
por: Truebestein, Linda, et al.
Publicado: (2021)

TRPV6 alleles do not influence prostate cancer progression
por: Kessler, Thorsten, et al.
Publicado: (2009)

PIP(2) depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
por: Harraz, Osama F, et al.
Publicado: (2018)

Cytoplasmic Autoinhibition in HCN Channels is Regulated by the Transmembrane Region
por: Page, Dana A., et al.
Publicado: (2020)

Additional data for the mouse TRPV6 expression atlas
por: Wartenberg, Philipp, et al.
Publicado: (2022)

The TRPV2 channel mediates Ca2+ influx and the Δ9-THC-dependent decrease in osmotic fragility in red blood cells
por: Belkacemi, Anouar, et al.
Publicado: (2021)

PIP(2) Activates TRPV5 and Releases Its Inhibition by Intracellular Mg(2+)
por: Lee, Jason, et al.
Publicado: (2005)

Ion permeation controlled by hydrophobic residues and proton binding in the proton-activated chloride channel
por: Cai, Ruiqi, et al.
Publicado: (2021)

Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy
por: Huang, Yuan, et al.
Publicado: (2020)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Tuning Protein Autoinhibition by Domain Destabilization
por: Cho, Jae-Hyun, et al.
Publicado: (2011)

Control of mRNA decapping by autoinhibition
por: Paquette, David R, et al.
Publicado: (2018)

DCLK1 autoinhibition and activation in tumorigenesis
por: Cheng, Linna, et al.
Publicado: (2021)

The role of TRPV1 channels in atherosclerosis
por: Zhang, Chenyang, et al.
Publicado: (2020)

PKC regulation of ion channels: The involvement of PIP(2)
por: Gada, Kirin D., et al.
Publicado: (2022)

A bibliometrics analysis and visualization study of TRPV1 channel
por: Gao, Ning, et al.
Publicado: (2023)

Autoinhibited transient, gated, and cascaded dynamic transcription of RNAs
por: Li, Zhenzhen, et al.
Publicado: (2022)

Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain
por: Wang, Xin, et al.
Publicado: (2014)

TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
por: Huang, Susan M, et al.
Publicado: (2011)

Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
por: Wu, Jing-Xiang, et al.
Publicado: (2015)

TRPV6 and Ca(v)1.3 Mediate Distal Small Intestine Calcium Absorption Before Weaning
por: Beggs, Megan R., et al.
Publicado: (2019)

Structural Basis for ESCRT-III Protein Autoinhibition
por: Bajorek, Monika, et al.
Publicado: (2009)

Autoinhibition by Iodide Ion in the Methionine–Iodine Reaction
por: Xu, Li, et al.
Publicado: (2020)

The Architecture of Talin1 Reveals an Autoinhibition Mechanism
por: Dedden, Dirk, et al.
Publicado: (2019)

Allosteric regulation of autoinhibition and activation of c-Abl
por: Liu, Yonglan, et al.
Publicado: (2022)

Structure of LRRK1 and mechanisms of autoinhibition and activation
por: Reimer, Janice M., et al.
Publicado: (2023)

Little PIP, little PIP, let me in
por: LeBrasseur, Nicole
Publicado: (2002)

Dual Regulation of Voltage-Sensitive Ion Channels by PIP(2)
por: Rodríguez-Menchaca, Aldo A., et al.
Publicado: (2012)

The where and how of PIP regulation of cone photoreceptor CNG channels
por: Zhou, Lei, et al.
Publicado: (2013)

PIP(2) regulation of TRPC5 channel activation and desensitization
por: Ningoo, Mehek, et al.
Publicado: (2021)

Inhibition of the proton-activated chloride channel PAC by PIP(2)
por: Mihaljević, Ljubica, et al.
Publicado: (2023)

The pip1s Quintuple Mutants Demonstrate the Essential Roles of PIP1s in the Plant Growth and Development of Arabidopsis
por: Wang, Xing, et al.
Publicado: (2021)

Functional TRPV2 and TRPV4 channels in human cardiac c‐kit(+) progenitor cells
por: Che, Hui, et al.
Publicado: (2016)

Blockade of TRPV channels by intracellular spermine
por: Maksaev, Grigory, et al.
Publicado: (2023)

Transient Receptor Potential Vanilloid 6 (TRPV6) Proteins Control the Extracellular Matrix Structure of the Placental Labyrinth
por: Winter, Manuel, et al.
Publicado: (2020)

Evidence for functional coupling of cGMP/cGKI signalling and TRPC channels in endothelium but not in vascular smooth muscle
por: Loga, Florian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pn72h6o1k1gvoa3j05apgnttf3