Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion

Aberrantly activated kinase signaling pathways drive invasion and dissemination in medulloblastoma (MB). A majority of tumor-promoting kinase signaling pathways feed into the mitogen-activated protein kinase (MAPK) extracellular regulated kinase (ERK1/2) pathway. The activation status of ERK1/2 duri...

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Detalles Bibliográficos
Autores principales: Schönholzer, Marc Thomas, Migliavacca, Jessica, Alvarez, Elena, Santhana Kumar, Karthiga, Neve, Anuja, Gries, Alexandre, Ma, Min, Grotzer, Michael A., Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452206/
https://www.ncbi.nlm.nih.gov/pubmed/32818841
http://dx.doi.org/10.1016/j.neo.2020.07.006

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