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Miliary pattern, a classic pulmonary finding of tuberculosis disease
INTRODUCTION: The increase in age of the population and in the use of immunosuppressive treatment makes tuberculosis (TB) with hematogenous or lymphatic dissemination a current problem. METHODS: We collected all the patients diagnosed with tuberculosis with miliary pulmonary pattern at the Santiago...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452224/ https://www.ncbi.nlm.nih.gov/pubmed/32904186 http://dx.doi.org/10.1016/j.jctube.2020.100179 |
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author | Alende-Castro, Vanesa Macía-Rodríguez, Cristina Páez-Guillán, Emilio García-Villafranca, Alba |
author_facet | Alende-Castro, Vanesa Macía-Rodríguez, Cristina Páez-Guillán, Emilio García-Villafranca, Alba |
author_sort | Alende-Castro, Vanesa |
collection | PubMed |
description | INTRODUCTION: The increase in age of the population and in the use of immunosuppressive treatment makes tuberculosis (TB) with hematogenous or lymphatic dissemination a current problem. METHODS: We collected all the patients diagnosed with tuberculosis with miliary pulmonary pattern at the Santiago de Compostela University Teaching Hospital (NW Spain) from 1 January 2006 to 31 December 2015. RESULTS: A total of 27 patients were included, 70.4% women, with a median age of 69.0 years old. A cause of immunosuppression was observed only in 51.9% of patients. The majority of the cases (65.0%) presented pulmonary affectation. The most frequently isolated species was Mycobacterium tuberculosis (88.9%). Multiresistance to first-line antituberculosis drugs was observed only in 3.7%. 92.6% of the patients received treatment with Isoniazid, Rifampicin and Pyrazinamine, associated in 48.1% of them with Ethambutol. Two patients died during admission and there were no recurrences in the 2-years follow-up. CONCLUSIONS: Miliary tuberculosis remains a current pathology. Most patients do not have a known cause of immunosuppression. The response to the typical treatment is usually good. |
format | Online Article Text |
id | pubmed-7452224 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-74522242020-09-03 Miliary pattern, a classic pulmonary finding of tuberculosis disease Alende-Castro, Vanesa Macía-Rodríguez, Cristina Páez-Guillán, Emilio García-Villafranca, Alba J Clin Tuberc Other Mycobact Dis Article INTRODUCTION: The increase in age of the population and in the use of immunosuppressive treatment makes tuberculosis (TB) with hematogenous or lymphatic dissemination a current problem. METHODS: We collected all the patients diagnosed with tuberculosis with miliary pulmonary pattern at the Santiago de Compostela University Teaching Hospital (NW Spain) from 1 January 2006 to 31 December 2015. RESULTS: A total of 27 patients were included, 70.4% women, with a median age of 69.0 years old. A cause of immunosuppression was observed only in 51.9% of patients. The majority of the cases (65.0%) presented pulmonary affectation. The most frequently isolated species was Mycobacterium tuberculosis (88.9%). Multiresistance to first-line antituberculosis drugs was observed only in 3.7%. 92.6% of the patients received treatment with Isoniazid, Rifampicin and Pyrazinamine, associated in 48.1% of them with Ethambutol. Two patients died during admission and there were no recurrences in the 2-years follow-up. CONCLUSIONS: Miliary tuberculosis remains a current pathology. Most patients do not have a known cause of immunosuppression. The response to the typical treatment is usually good. Elsevier 2020-08-11 /pmc/articles/PMC7452224/ /pubmed/32904186 http://dx.doi.org/10.1016/j.jctube.2020.100179 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Alende-Castro, Vanesa Macía-Rodríguez, Cristina Páez-Guillán, Emilio García-Villafranca, Alba Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title | Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title_full | Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title_fullStr | Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title_full_unstemmed | Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title_short | Miliary pattern, a classic pulmonary finding of tuberculosis disease |
title_sort | miliary pattern, a classic pulmonary finding of tuberculosis disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452224/ https://www.ncbi.nlm.nih.gov/pubmed/32904186 http://dx.doi.org/10.1016/j.jctube.2020.100179 |
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