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SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12

Mitochondrial DNA (mtDNA) encodes thirteen core components of OXPHOS complexes, and its steady expression is crucial for cellular energy homeostasis. However, the regulation of mtDNA expression machinery, along with its sensing mechanism to energetic stresses, is not fully understood. Here, we ident...

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Detalles Bibliográficos
Autores principales: Ma, Yuan, Zhu, Suwei, Lv, Tingting, Gu, Xia, Feng, Hong, Zhen, Junhui, Xin, Wei, Wan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452302/
https://www.ncbi.nlm.nih.gov/pubmed/32805647
http://dx.doi.org/10.1016/j.isci.2020.101428

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