Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis

One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimi...

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Detalles Bibliográficos
Autores principales: Lin, Hsin-Pin, Lieberman, Leora, Patel, Mitesh, Chuquilin, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452392/
https://www.ncbi.nlm.nih.gov/pubmed/32885084
http://dx.doi.org/10.1016/j.heliyon.2020.e04769
Descripción
Sumario:One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimic motor neuron disease. Here, we describe a patient with SCC of the base of the tongue related to human papillomavirus infection who was initially misdiagnosed with bulbar-onset ALS.

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