Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis

One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimi...

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Autores principales: Lin, Hsin-Pin, Lieberman, Leora, Patel, Mitesh, Chuquilin, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452392/
https://www.ncbi.nlm.nih.gov/pubmed/32885084
http://dx.doi.org/10.1016/j.heliyon.2020.e04769
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author Lin, Hsin-Pin
Lieberman, Leora
Patel, Mitesh
Chuquilin, Miguel
author_facet Lin, Hsin-Pin
Lieberman, Leora
Patel, Mitesh
Chuquilin, Miguel
author_sort Lin, Hsin-Pin
collection PubMed
description One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimic motor neuron disease. Here, we describe a patient with SCC of the base of the tongue related to human papillomavirus infection who was initially misdiagnosed with bulbar-onset ALS.
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spelling pubmed-74523922020-09-02 Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis Lin, Hsin-Pin Lieberman, Leora Patel, Mitesh Chuquilin, Miguel Heliyon Article One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimic motor neuron disease. Here, we describe a patient with SCC of the base of the tongue related to human papillomavirus infection who was initially misdiagnosed with bulbar-onset ALS. Elsevier 2020-08-24 /pmc/articles/PMC7452392/ /pubmed/32885084 http://dx.doi.org/10.1016/j.heliyon.2020.e04769 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Lin, Hsin-Pin
Lieberman, Leora
Patel, Mitesh
Chuquilin, Miguel
Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title_full Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title_fullStr Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title_full_unstemmed Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title_short Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
title_sort squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452392/
https://www.ncbi.nlm.nih.gov/pubmed/32885084
http://dx.doi.org/10.1016/j.heliyon.2020.e04769
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AT patelmitesh squamouscellcarcinomaofthebaseofthetonguemimickingbulbaronsetamyotrophiclateralsclerosis
AT chuquilinmiguel squamouscellcarcinomaofthebaseofthetonguemimickingbulbaronsetamyotrophiclateralsclerosis

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