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Tramadol enhances PGF(2α)-stimulated osteoprotegerin synthesis in osteoblasts

Osteoprotegerin (OPG) synthesized by osteoblasts is currently considered a crucial regulator to suppress the formation and function of osteoclasts. We previously showed that the synthesis of OPG is stimulated by prostaglandin F(2α) (PGF(2α)) in the involvement of p38 mitogen-activated protein kinase...

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Detalles Bibliográficos
Autores principales: Kim, Woo, Tanabe, Kumiko, Kuroyanagi, Gen, Matsushima-Nishiwaki, Rie, Fujita, Kazuhiko, Kawabata, Tetsu, Sakai, Go, Tachi, Junko, Hioki, Tomoyuki, Nakashima, Daiki, Yamaguchi, Shinobu, Otsuka, Takanobu, Tokuda, Haruhiko, Kozawa, Osamu, Iida, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452493/
https://www.ncbi.nlm.nih.gov/pubmed/32904295
http://dx.doi.org/10.1016/j.heliyon.2020.e04779