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Tramadol enhances PGF(2α)-stimulated osteoprotegerin synthesis in osteoblasts
Osteoprotegerin (OPG) synthesized by osteoblasts is currently considered a crucial regulator to suppress the formation and function of osteoclasts. We previously showed that the synthesis of OPG is stimulated by prostaglandin F(2α) (PGF(2α)) in the involvement of p38 mitogen-activated protein kinase...
Autores principales: | Kim, Woo, Tanabe, Kumiko, Kuroyanagi, Gen, Matsushima-Nishiwaki, Rie, Fujita, Kazuhiko, Kawabata, Tetsu, Sakai, Go, Tachi, Junko, Hioki, Tomoyuki, Nakashima, Daiki, Yamaguchi, Shinobu, Otsuka, Takanobu, Tokuda, Haruhiko, Kozawa, Osamu, Iida, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452493/ https://www.ncbi.nlm.nih.gov/pubmed/32904295 http://dx.doi.org/10.1016/j.heliyon.2020.e04779 |
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