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Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study

BACKGROUND: Tumour necrosis factor (TNF) inhibitors are used in the treatment of certain autoimmune diseases but given the role of TNF in tumour biology and atherosclerosis, such therapies may influence the risk of cancer and cardiovascular disease. We conducted a Mendelian randomization study to ex...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Carter, Paul, Bruzelius, Maria, Vithayathil, Mathew, Kar, Siddhartha, Mason, Amy M., Lin, Ang, Burgess, Stephen, Larsson, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452586/
https://www.ncbi.nlm.nih.gov/pubmed/32805626
http://dx.doi.org/10.1016/j.ebiom.2020.102956