A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort

This manuscript aims to present a treatment algorithm we applied to manage COVID-19 patients admitted to our hospital. During the study period, 2043 patients with suspected COVID-19 were admitted to the emergency department. Molecular tests indicated that 475 of these patients tested positive for CO...

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Detalles Bibliográficos
Autores principales: Cag, Yasemin, Icten, Sacit, Isik-Goren, Burcu, Baysal, Naciye Betul, Bektas, Begum, Selvi, Ece, Ergen, Pinar, Aydin, Ozlem, Ucisik, Ayse Canan, Yilmaz-Karadag, Fatma, Caskurlu, Hulya, Akarsu-Ayazoglu, Tulin, Kocoglu, Hasan, Uzman, Sinan, Nural-Pamukcu, Muge, Arslan, Ferhat, Bas, Gurhan, Kalcioglu, Mahmut Tayyar, Vahaboglu, Haluk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452614/
https://www.ncbi.nlm.nih.gov/pubmed/32856202
http://dx.doi.org/10.1007/s10096-020-04016-1
Descripción
Sumario:This manuscript aims to present a treatment algorithm we applied to manage COVID-19 patients admitted to our hospital. During the study period, 2043 patients with suspected COVID-19 were admitted to the emergency department. Molecular tests indicated that 475 of these patients tested positive for COVID-19. We administered hydroxychloroquine plus doxycycline to mild cases (isolated at home) for 3 days and lopinavir plus doxycycline to moderate and severe cases (hospitalized) for 5 days. The overall case fatality rate was 4.2% (20/475).

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