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A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort
This manuscript aims to present a treatment algorithm we applied to manage COVID-19 patients admitted to our hospital. During the study period, 2043 patients with suspected COVID-19 were admitted to the emergency department. Molecular tests indicated that 475 of these patients tested positive for CO...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452614/ https://www.ncbi.nlm.nih.gov/pubmed/32856202 http://dx.doi.org/10.1007/s10096-020-04016-1 |
| _version_ | 1783575194482245632 |
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| author | Cag, Yasemin Icten, Sacit Isik-Goren, Burcu Baysal, Naciye Betul Bektas, Begum Selvi, Ece Ergen, Pinar Aydin, Ozlem Ucisik, Ayse Canan Yilmaz-Karadag, Fatma Caskurlu, Hulya Akarsu-Ayazoglu, Tulin Kocoglu, Hasan Uzman, Sinan Nural-Pamukcu, Muge Arslan, Ferhat Bas, Gurhan Kalcioglu, Mahmut Tayyar Vahaboglu, Haluk |
| author_facet | Cag, Yasemin Icten, Sacit Isik-Goren, Burcu Baysal, Naciye Betul Bektas, Begum Selvi, Ece Ergen, Pinar Aydin, Ozlem Ucisik, Ayse Canan Yilmaz-Karadag, Fatma Caskurlu, Hulya Akarsu-Ayazoglu, Tulin Kocoglu, Hasan Uzman, Sinan Nural-Pamukcu, Muge Arslan, Ferhat Bas, Gurhan Kalcioglu, Mahmut Tayyar Vahaboglu, Haluk |
| author_sort | Cag, Yasemin |
| collection | PubMed |
| description | This manuscript aims to present a treatment algorithm we applied to manage COVID-19 patients admitted to our hospital. During the study period, 2043 patients with suspected COVID-19 were admitted to the emergency department. Molecular tests indicated that 475 of these patients tested positive for COVID-19. We administered hydroxychloroquine plus doxycycline to mild cases (isolated at home) for 3 days and lopinavir plus doxycycline to moderate and severe cases (hospitalized) for 5 days. The overall case fatality rate was 4.2% (20/475). |
| format | Online Article Text |
| id | pubmed-7452614 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Springer Berlin Heidelberg |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-74526142020-08-28 A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort Cag, Yasemin Icten, Sacit Isik-Goren, Burcu Baysal, Naciye Betul Bektas, Begum Selvi, Ece Ergen, Pinar Aydin, Ozlem Ucisik, Ayse Canan Yilmaz-Karadag, Fatma Caskurlu, Hulya Akarsu-Ayazoglu, Tulin Kocoglu, Hasan Uzman, Sinan Nural-Pamukcu, Muge Arslan, Ferhat Bas, Gurhan Kalcioglu, Mahmut Tayyar Vahaboglu, Haluk Eur J Clin Microbiol Infect Dis Brief Report This manuscript aims to present a treatment algorithm we applied to manage COVID-19 patients admitted to our hospital. During the study period, 2043 patients with suspected COVID-19 were admitted to the emergency department. Molecular tests indicated that 475 of these patients tested positive for COVID-19. We administered hydroxychloroquine plus doxycycline to mild cases (isolated at home) for 3 days and lopinavir plus doxycycline to moderate and severe cases (hospitalized) for 5 days. The overall case fatality rate was 4.2% (20/475). Springer Berlin Heidelberg 2020-08-27 2021 /pmc/articles/PMC7452614/ /pubmed/32856202 http://dx.doi.org/10.1007/s10096-020-04016-1 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Brief Report Cag, Yasemin Icten, Sacit Isik-Goren, Burcu Baysal, Naciye Betul Bektas, Begum Selvi, Ece Ergen, Pinar Aydin, Ozlem Ucisik, Ayse Canan Yilmaz-Karadag, Fatma Caskurlu, Hulya Akarsu-Ayazoglu, Tulin Kocoglu, Hasan Uzman, Sinan Nural-Pamukcu, Muge Arslan, Ferhat Bas, Gurhan Kalcioglu, Mahmut Tayyar Vahaboglu, Haluk A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title | A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title_full | A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title_fullStr | A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title_full_unstemmed | A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title_short | A novel approach to managing COVID-19 patients; results of lopinavir plus doxycycline cohort |
| title_sort | novel approach to managing covid-19 patients; results of lopinavir plus doxycycline cohort |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452614/ https://www.ncbi.nlm.nih.gov/pubmed/32856202 http://dx.doi.org/10.1007/s10096-020-04016-1 |
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