Plerixafor combined with standard regimens for hematopoietic stem cell mobilization in pediatric patients with solid tumors eligible for autologous transplants: two-arm phase I/II study (MOZAIC)

This study (NCT01288573) investigated plerixafor’s safety and efficacy in children with cancer. Stage 1 investigated the dosage, pharmacokinetics (PK), pharmacodynamics (PD), and safety of plerixafor + standard mobilization (G-CSF ± chemotherapy). The stage 2 primary endpoint was successful mobiliza...

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Detalles Bibliográficos
Autores principales: Morland, Bruce, Kepak, Tomas, Dallorso, Sandro, Sevilla, Julian, Murphy, Dermot, Luksch, Roberto, Yaniv, Isaac, Bader, Peter, Rößler, Jochen, Bisogno, Gianni, Maecker-Kolhoff, Britta, Lang, Peter, Zwaan, C. Michel, Sumerauer, David, Kriván, Gergely, Bernard, John, Liu, Qianying, Doyle, Eileen, Locatelli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452813/
https://www.ncbi.nlm.nih.gov/pubmed/32127657
http://dx.doi.org/10.1038/s41409-020-0836-2

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