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Systemic Treatment With Nicotinamide Riboside Is Protective in a Mouse Model of Light-Induced Retinal Degeneration

PURPOSE: Maintaining levels of nicotinamide adenine dinucleotide (NAD(+)), a coenzyme critical for cellular energetics and biosynthetic pathways, may be therapeutic in retinal disease because retinal NAD(+) levels decline during retinal damage and degeneration. The purpose of this study was to inves...

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Detalles Bibliográficos
Autores principales:	Zhang, Xian, Henneman, Nathaniel F., Girardot, Preston E., Sellers, Jana T., Chrenek, Micah A., Li, Ying, Wang, Jiaxing, Brenner, Charles, Nickerson, John M., Boatright, Jeffrey H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452859/ https://www.ncbi.nlm.nih.gov/pubmed/32852543 http://dx.doi.org/10.1167/iovs.61.10.47

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