A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin

Hypoxia-inducible factor (HIF), an αβ dimer, is the master regulator of oxygen homeostasis with hundreds of hypoxia-inducible target genes. Three HIF isoforms differing in the oxygen-sensitive α subunit exist in vertebrates. While HIF-1 and HIF-2 are known transcription activators, HIF-3 has been co...

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Detalles Bibliográficos
Autores principales: Tolonen, Jussi-Pekka, Heikkilä, Minna, Malinen, Marjo, Lee, Hang-Mao, Palvimo, Jorma J., Wei, Gong-Hong, Myllyharju, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452874/
https://www.ncbi.nlm.nih.gov/pubmed/31768607
http://dx.doi.org/10.1007/s00018-019-03387-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452874/
https://www.ncbi.nlm.nih.gov/pubmed/31768607
http://dx.doi.org/10.1007/s00018-019-03387-9

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