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Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in

In mammalian cells, long noncoding RNAs (lncRNAs) form complexes with proteins to execute various biological functions such as gene transcription, RNA processing and other signaling activities. However, methods to track endogenous lncRNA dynamics in live cells and screen for lncRNA interacting prote...

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Detalles Bibliográficos
Autores principales:	Chen, Bohong, Deng, Shengcheng, Ge, Tianyu, Ye, Miaoman, Yu, Jianping, Lin, Song, Ma, Wenbin, Songyang, Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452982/ https://www.ncbi.nlm.nih.gov/pubmed/32458346 http://dx.doi.org/10.1007/s13238-020-00706-w

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