Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells

The periodic cartilage and smooth muscle structures in mammalian trachea are derived from tracheal mesoderm, and tracheal malformations result in serious respiratory defects in neonates. Here we show that canonical Wnt signaling in mesoderm is critical to confer trachea mesenchymal identity in human...

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Detalles Bibliográficos
Autores principales: Kishimoto, Keishi, Furukawa, Kana T., Luz-Madrigal, Agustin, Yamaoka, Akira, Matsuoka, Chisa, Habu, Masanobu, Alev, Cantas, Zorn, Aaron M., Morimoto, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453000/
https://www.ncbi.nlm.nih.gov/pubmed/32855415
http://dx.doi.org/10.1038/s41467-020-17969-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453000/
https://www.ncbi.nlm.nih.gov/pubmed/32855415
http://dx.doi.org/10.1038/s41467-020-17969-w

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