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Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells
The periodic cartilage and smooth muscle structures in mammalian trachea are derived from tracheal mesoderm, and tracheal malformations result in serious respiratory defects in neonates. Here we show that canonical Wnt signaling in mesoderm is critical to confer trachea mesenchymal identity in human...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453000/ https://www.ncbi.nlm.nih.gov/pubmed/32855415 http://dx.doi.org/10.1038/s41467-020-17969-w |