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RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
Oligomeric assemblies of tau and the RNA-binding proteins (RBPs) Musashi (MSI) are reported in Alzheimer’s disease (AD). However, the role of MSI and tau interaction in their aggregation process and its effects are nor clearly known in neurodegenerative diseases. Here, we investigated the expression...
Autores principales: | Montalbano, Mauro, McAllen, Salome, Puangmalai, Nicha, Sengupta, Urmi, Bhatt, Nemil, Johnson, Omar D., Kharas, Michael G., Kayed, Rakez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453003/ https://www.ncbi.nlm.nih.gov/pubmed/32855391 http://dx.doi.org/10.1038/s41467-020-18022-6 |
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