Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas

Intracellular galectins are carbohydrate-binding proteins capable of sensing and repairing damaged lysosomes. As in the physiological conditions glycosylated moieties are mostly in the lysosomal lumen but not cytosol, it is unclear whether galectins reside in lysosomes, bind to glycosylated proteins...

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Detalles Bibliográficos
Autores principales: Sudhakar, Janaki N., Lu, Hsueh-Han, Chiang, Hung-Yu, Suen, Ching-Shu, Hwang, Ming-Jing, Wu, Sung-Yu, Shen, Chia-Ning, Chang, Yao-Ming, Li, Fu-An, Liu, Fu-Tong, Shui, Jr-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453023/
https://www.ncbi.nlm.nih.gov/pubmed/32855403
http://dx.doi.org/10.1038/s41467-020-18102-7

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