Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson’s disease

BACKGROUND: Parkinson’s disease is associated with severe nigro-striatal dopamine depletion, leading to motor dysfunction and altered reward processing. We previously showed that drug-naïve patients with Parkinson’s disease had a consistent attenuation of reward signalling in the mesolimbic and meso...

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Detalles Bibliográficos
Autores principales: van der Vegt, Joyce P.M., Hulme, Oliver J., Madsen, Kristoffer H., Buhmann, Carsten, Bloem, Bastiaan R., Münchau, Alexander, Helmich, Rick C., Siebner, Hartwig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453137/
https://www.ncbi.nlm.nih.gov/pubmed/32798910
http://dx.doi.org/10.1016/j.nicl.2020.102362

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