SIRT1 Mediates Neuropathic Pain Induced by Sciatic Nerve Chronic Constrictive Injury in the VTA-NAc Pathway

BACKGROUND: Mounting evidence has shown that sirtuin 1 (SIRT1), a class III histone deacetylase, alleviated several types of neuropathic pain in the spinal cord and dorsal root ganglion and regulated some aberrant behaviors in the ventral tegmental area (VTA) and the nucleus accumbens (NAc). METHODS...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Wang, Lei, Zhang, Guotao, Qiao, Xueli, Zhang, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453274/
https://www.ncbi.nlm.nih.gov/pubmed/32922581
http://dx.doi.org/10.1155/2020/4245968

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