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Modulating Lipoprotein Transcellular Transport and Atherosclerotic Plaque Formation in ApoE(–/–) Mice via Nanoformulated Lipid–Methotrexate Conjugates

[Image: see text] Macrophage inflammation and maturation into foam cells, following the engulfment of oxidized low-density lipoproteins (oxLDL), are major hallmarks in the onset and progression of atherosclerosis. Yet, chronic treatments with anti-inflammatory agents, such as methotrexate (MTX), fai...

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Detalles Bibliográficos
Autores principales:	Di Francesco, Valentina, Gurgone, Danila, Palomba, Roberto, Ferreira, Miguel Filipe Moreira Marques, Catelani, Tiziano, Cervadoro, Antonio, Maffia, Pasquale, Decuzzi, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453397/ https://www.ncbi.nlm.nih.gov/pubmed/32805983 http://dx.doi.org/10.1021/acsami.0c12202

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