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Downregulation of lncRNA H19 alleviates atherosclerosis through inducing the apoptosis of vascular smooth muscle cells

Aberrant proliferation and apoptosis of vascular smooth muscle cells (VSMCs) serve a dominant role in the pathogenesis of atherosclerosis (AS). Long non-coding (lnc)RNA H19 is reported to accelerate the progression of AS by inhibiting the apoptosis of VSMCs, whereas p53 is identified as promoting VS...

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Detalles Bibliográficos
Autores principales: Sun, Hui, Jiang, Qianqian, Sheng, Li, Cui, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453499/
https://www.ncbi.nlm.nih.gov/pubmed/32945413
http://dx.doi.org/10.3892/mmr.2020.11394