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Erastin induces apoptotic and ferroptotic cell death by inducing ROS accumulation by causing mitochondrial dysfunction in gastric cancer cell HGC-27

Erastin, a classical inducer of non-apoptotic cell death, exerts cytotoxicity in several types of cancer cells, including gastric cancer cells, by depleting glutathione, which is a primary cellular antioxidant, thus causing reactive oxygen species (ROS) accumulation. Although numerous studies have f...

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Detalles Bibliográficos
Autores principales:	Sun, Yingwei, Deng, Rongrong, Zhang, Cuiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453531/ https://www.ncbi.nlm.nih.gov/pubmed/32945484 http://dx.doi.org/10.3892/mmr.2020.11376

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