Excess diacylglycerol at the endoplasmic reticulum disrupts endomembrane homeostasis and autophagy

BACKGROUND: When stressed, eukaryotic cells produce triacylglycerol (TAG) to store nutrients and mobilize autophagy to combat internal damage. We and others previously reported that in yeast, elimination of TAG synthesizing enzymes inhibits autophagy under nitrogen starvation, yet the underlying mec...

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Detalles Bibliográficos
Autores principales: Li, Dan, Yang, Shu-Gao, He, Cheng-Wen, Zhang, Zheng-Tan, Liang, Yongheng, Li, Hui, Zhu, Jing, Su, Xiong, Gong, Qingqiu, Xie, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453538/
https://www.ncbi.nlm.nih.gov/pubmed/32859196
http://dx.doi.org/10.1186/s12915-020-00837-w

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