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Single immunoglobulin and Toll-interleukin-1 receptor domain containing molecule protects against severe acute pancreatitis in vitro by negatively regulating the Toll-like receptor-4 signaling pathway: A clinical and experimental study

Single immunoglobulin and Toll-interleukin-1 receptor domain-containing molecule (SIGIRR) is a specific inhibitor of IL-1R and Toll-like receptor (TLR) signaling and considered a potential target for the treatment of inflammatory diseases. Pathogenic mechanisms associated with the TLR4 signaling pat...

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Detalles Bibliográficos
Autores principales: Zhao, Rulin, Song, Conghua, Liu, Li, Liu, Qiong, Zhou, Nanjin, Zhou, Xiaojiang, Xie, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453662/
https://www.ncbi.nlm.nih.gov/pubmed/32945488
http://dx.doi.org/10.3892/mmr.2020.11379