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Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment

BACKGROUND: Subjective cognitive difficulties are common in mental illness and have a negative impact on role functioning. Little is understood about subjective cognition and the longitudinal relationship with depression and anxiety symptoms in young people. AIMS: To examine the relationship between...

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Autores principales: Allott, Kelly, Gao, Caroline, Hetrick, Sarah E., Filia, Kate M., Menssink, Jana M., Fisher, Caroline, Hickie, Ian B., Herrman, Helen E., Rickwood, Debra J., Parker, Alexandra G., Mcgorry, Patrick D., Cotton, Sue M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453798/
https://www.ncbi.nlm.nih.gov/pubmed/32753079
http://dx.doi.org/10.1192/bjo.2020.68
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author Allott, Kelly
Gao, Caroline
Hetrick, Sarah E.
Filia, Kate M.
Menssink, Jana M.
Fisher, Caroline
Hickie, Ian B.
Herrman, Helen E.
Rickwood, Debra J.
Parker, Alexandra G.
Mcgorry, Patrick D.
Cotton, Sue M.
author_facet Allott, Kelly
Gao, Caroline
Hetrick, Sarah E.
Filia, Kate M.
Menssink, Jana M.
Fisher, Caroline
Hickie, Ian B.
Herrman, Helen E.
Rickwood, Debra J.
Parker, Alexandra G.
Mcgorry, Patrick D.
Cotton, Sue M.
author_sort Allott, Kelly
collection PubMed
description BACKGROUND: Subjective cognitive difficulties are common in mental illness and have a negative impact on role functioning. Little is understood about subjective cognition and the longitudinal relationship with depression and anxiety symptoms in young people. AIMS: To examine the relationship between changes in levels of depression and anxiety and changes in subjective cognitive functioning over 3 months in help-seeking youth. METHOD: This was a cohort study of 656 youth aged 12–25 years attending Australian headspace primary mental health services. Subjective changes in cognitive functioning (rated as better, same, worse) reported after 3 months of treatment was assessed using the Neuropsychological Symptom Self-Report. Multivariate multinomial logistic regression analysis was conducted to evaluate the impact of baseline levels of and changes in depression (nine-item Patient Health Questionnaire; PHQ9) and anxiety symptoms (seven-item Generalised Anxiety Disorder scale; GAD7) on changes in subjective cognitive function at follow-up while controlling for covariates. RESULTS: With a one-point reduction in PHQ9 at follow-up, there was an estimated 11–18% increase in ratings of better subjective cognitive functioning at follow-up, relative to stable cognitive functioning. A one-point increase in PHQ9 from baseline to follow-up was associated with 7–14% increase in ratings of worse subjective cognitive functioning over 3 months, relative to stable cognitive functioning. A similar attenuated pattern of findings was observed for the GAD7. CONCLUSIONS: A clear association exists between subjective cognitive functioning outcomes and changes in self-reported severity of affective symptoms in young people over the first 3 months of treatment. Understanding the timing and mechanisms of these associations is needed to tailor treatment.
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spelling pubmed-74537982020-09-11 Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment Allott, Kelly Gao, Caroline Hetrick, Sarah E. Filia, Kate M. Menssink, Jana M. Fisher, Caroline Hickie, Ian B. Herrman, Helen E. Rickwood, Debra J. Parker, Alexandra G. Mcgorry, Patrick D. Cotton, Sue M. BJPsych Open Papers BACKGROUND: Subjective cognitive difficulties are common in mental illness and have a negative impact on role functioning. Little is understood about subjective cognition and the longitudinal relationship with depression and anxiety symptoms in young people. AIMS: To examine the relationship between changes in levels of depression and anxiety and changes in subjective cognitive functioning over 3 months in help-seeking youth. METHOD: This was a cohort study of 656 youth aged 12–25 years attending Australian headspace primary mental health services. Subjective changes in cognitive functioning (rated as better, same, worse) reported after 3 months of treatment was assessed using the Neuropsychological Symptom Self-Report. Multivariate multinomial logistic regression analysis was conducted to evaluate the impact of baseline levels of and changes in depression (nine-item Patient Health Questionnaire; PHQ9) and anxiety symptoms (seven-item Generalised Anxiety Disorder scale; GAD7) on changes in subjective cognitive function at follow-up while controlling for covariates. RESULTS: With a one-point reduction in PHQ9 at follow-up, there was an estimated 11–18% increase in ratings of better subjective cognitive functioning at follow-up, relative to stable cognitive functioning. A one-point increase in PHQ9 from baseline to follow-up was associated with 7–14% increase in ratings of worse subjective cognitive functioning over 3 months, relative to stable cognitive functioning. A similar attenuated pattern of findings was observed for the GAD7. CONCLUSIONS: A clear association exists between subjective cognitive functioning outcomes and changes in self-reported severity of affective symptoms in young people over the first 3 months of treatment. Understanding the timing and mechanisms of these associations is needed to tailor treatment. Cambridge University Press 2020-08-05 /pmc/articles/PMC7453798/ /pubmed/32753079 http://dx.doi.org/10.1192/bjo.2020.68 Text en © The Author(s) 2020 http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Papers
Allott, Kelly
Gao, Caroline
Hetrick, Sarah E.
Filia, Kate M.
Menssink, Jana M.
Fisher, Caroline
Hickie, Ian B.
Herrman, Helen E.
Rickwood, Debra J.
Parker, Alexandra G.
Mcgorry, Patrick D.
Cotton, Sue M.
Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title_full Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title_fullStr Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title_full_unstemmed Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title_short Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
title_sort subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment
topic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453798/
https://www.ncbi.nlm.nih.gov/pubmed/32753079
http://dx.doi.org/10.1192/bjo.2020.68
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