Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses

Stress exposure is associated with the pathogenesis of psychiatric disorders, including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). Here, we show in rodents that chronic stress exposure rapidly and transiently elevates hippocampal expression of Kruppel-like factor 9 (K...

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Detalles Bibliográficos
Autores principales: Besnard, Antoine, Langberg, Tomer, Levinson, Sally, Chu, Duong, Vicidomini, Cinzia, Scobie, Kimberly N., Dwork, Andrew J., Arango, Victoria, Rosoklija, Gorazd B., Mann, J. John, Hen, René, Leonardo, E. David, Boldrini, Maura, Sahay, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453932/
https://www.ncbi.nlm.nih.gov/pubmed/29898391
http://dx.doi.org/10.1016/j.celrep.2018.05.040

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