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ACK1–AR and AR–HOXB13 signaling axes: epigenetic regulation of lethal prostate cancers

The androgen receptor (AR) is a critical transcription factor in prostate cancer (PC) pathogenesis. Its activity in malignant cells is dependent on interactions with a diverse set of co-regulators. These interactions fluctuate depending on androgen availability. For example, the androgen depletion i...

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Detalles Bibliográficos
Autores principales: Kim, Eric H, Cao, Dengfeng, Mahajan, Nupam P, Andriole, Gerald L, Mahajan, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454006/
https://www.ncbi.nlm.nih.gov/pubmed/32885168
http://dx.doi.org/10.1093/narcan/zcaa018