Cargando…

Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respirator...

Descripción completa

Detalles Bibliográficos
Autores principales: Adachi, Takuya, Chong, Ja-Mun, Nakajima, Noriko, Sano, Masahiro, Yamazaki, Jun, Miyamoto, Ippei, Nishioka, Haruka, Akita, Hidetaka, Sato, Yuko, Kataoka, Michiyo, Katano, Harutaka, Tobiume, Minoru, Sekizuka, Tsuyoshi, Itokawa, Kentaro, Kuroda, Makoto, Suzuki, Tadaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454070/
https://www.ncbi.nlm.nih.gov/pubmed/32412897
http://dx.doi.org/10.3201/eid2609.201353
_version_ 1783575454317281280
author Adachi, Takuya
Chong, Ja-Mun
Nakajima, Noriko
Sano, Masahiro
Yamazaki, Jun
Miyamoto, Ippei
Nishioka, Haruka
Akita, Hidetaka
Sato, Yuko
Kataoka, Michiyo
Katano, Harutaka
Tobiume, Minoru
Sekizuka, Tsuyoshi
Itokawa, Kentaro
Kuroda, Makoto
Suzuki, Tadaki
author_facet Adachi, Takuya
Chong, Ja-Mun
Nakajima, Noriko
Sano, Masahiro
Yamazaki, Jun
Miyamoto, Ippei
Nishioka, Haruka
Akita, Hidetaka
Sato, Yuko
Kataoka, Michiyo
Katano, Harutaka
Tobiume, Minoru
Sekizuka, Tsuyoshi
Itokawa, Kentaro
Kuroda, Makoto
Suzuki, Tadaki
author_sort Adachi, Takuya
collection PubMed
description An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells.
format Online
Article
Text
id pubmed-7454070
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-74540702020-09-03 Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan Adachi, Takuya Chong, Ja-Mun Nakajima, Noriko Sano, Masahiro Yamazaki, Jun Miyamoto, Ippei Nishioka, Haruka Akita, Hidetaka Sato, Yuko Kataoka, Michiyo Katano, Harutaka Tobiume, Minoru Sekizuka, Tsuyoshi Itokawa, Kentaro Kuroda, Makoto Suzuki, Tadaki Emerg Infect Dis Dispatch An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells. Centers for Disease Control and Prevention 2020-09 /pmc/articles/PMC7454070/ /pubmed/32412897 http://dx.doi.org/10.3201/eid2609.201353 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Adachi, Takuya
Chong, Ja-Mun
Nakajima, Noriko
Sano, Masahiro
Yamazaki, Jun
Miyamoto, Ippei
Nishioka, Haruka
Akita, Hidetaka
Sato, Yuko
Kataoka, Michiyo
Katano, Harutaka
Tobiume, Minoru
Sekizuka, Tsuyoshi
Itokawa, Kentaro
Kuroda, Makoto
Suzuki, Tadaki
Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title_full Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title_fullStr Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title_full_unstemmed Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title_short Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
title_sort clinicopathologic and immunohistochemical findings from autopsy of patient with covid-19, japan
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454070/
https://www.ncbi.nlm.nih.gov/pubmed/32412897
http://dx.doi.org/10.3201/eid2609.201353
work_keys_str_mv AT adachitakuya clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT chongjamun clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT nakajimanoriko clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT sanomasahiro clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT yamazakijun clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT miyamotoippei clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT nishiokaharuka clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT akitahidetaka clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT satoyuko clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT kataokamichiyo clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT katanoharutaka clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT tobiumeminoru clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT sekizukatsuyoshi clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT itokawakentaro clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT kurodamakoto clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan
AT suzukitadaki clinicopathologicandimmunohistochemicalfindingsfromautopsyofpatientwithcovid19japan