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Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France

We report a fatal case of measles inclusion-body encephalitis occurring in a woman from Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen shotgun metagenomic approach revealed a measles virus infection. We identified no mutations previously associated with...

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Autores principales: Rodriguez, Christophe, Gouilh, Meriadeg Ar, Weiss, Nicolas, Stroer, Sébastian, Mokhtari, Karima, Seilhean, Danielle, Mathon, Bertrand, Demontant, Vanessa, N’Debi, Melissa, Gricourt, Guillaume, Woerther, Paul-Louis, Pawlotsky, Jean-Michel, Stefic, Karl, Marlet, Julien, Dequin, Pierre-François, Guillon, Antoine, Pourcher, Valérie, Boutolleau, David, Vabret, Astrid, Burrel, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454109/
https://www.ncbi.nlm.nih.gov/pubmed/32818389
http://dx.doi.org/10.3201/eid2609.200366
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author Rodriguez, Christophe
Gouilh, Meriadeg Ar
Weiss, Nicolas
Stroer, Sébastian
Mokhtari, Karima
Seilhean, Danielle
Mathon, Bertrand
Demontant, Vanessa
N’Debi, Melissa
Gricourt, Guillaume
Woerther, Paul-Louis
Pawlotsky, Jean-Michel
Stefic, Karl
Marlet, Julien
Dequin, Pierre-François
Guillon, Antoine
Pourcher, Valérie
Boutolleau, David
Vabret, Astrid
Burrel, Sonia
author_facet Rodriguez, Christophe
Gouilh, Meriadeg Ar
Weiss, Nicolas
Stroer, Sébastian
Mokhtari, Karima
Seilhean, Danielle
Mathon, Bertrand
Demontant, Vanessa
N’Debi, Melissa
Gricourt, Guillaume
Woerther, Paul-Louis
Pawlotsky, Jean-Michel
Stefic, Karl
Marlet, Julien
Dequin, Pierre-François
Guillon, Antoine
Pourcher, Valérie
Boutolleau, David
Vabret, Astrid
Burrel, Sonia
author_sort Rodriguez, Christophe
collection PubMed
description We report a fatal case of measles inclusion-body encephalitis occurring in a woman from Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen shotgun metagenomic approach revealed a measles virus infection. We identified no mutations previously associated with neurovirulence.
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spelling pubmed-74541092020-09-03 Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France Rodriguez, Christophe Gouilh, Meriadeg Ar Weiss, Nicolas Stroer, Sébastian Mokhtari, Karima Seilhean, Danielle Mathon, Bertrand Demontant, Vanessa N’Debi, Melissa Gricourt, Guillaume Woerther, Paul-Louis Pawlotsky, Jean-Michel Stefic, Karl Marlet, Julien Dequin, Pierre-François Guillon, Antoine Pourcher, Valérie Boutolleau, David Vabret, Astrid Burrel, Sonia Emerg Infect Dis Dispatch We report a fatal case of measles inclusion-body encephalitis occurring in a woman from Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen shotgun metagenomic approach revealed a measles virus infection. We identified no mutations previously associated with neurovirulence. Centers for Disease Control and Prevention 2020-09 /pmc/articles/PMC7454109/ /pubmed/32818389 http://dx.doi.org/10.3201/eid2609.200366 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Rodriguez, Christophe
Gouilh, Meriadeg Ar
Weiss, Nicolas
Stroer, Sébastian
Mokhtari, Karima
Seilhean, Danielle
Mathon, Bertrand
Demontant, Vanessa
N’Debi, Melissa
Gricourt, Guillaume
Woerther, Paul-Louis
Pawlotsky, Jean-Michel
Stefic, Karl
Marlet, Julien
Dequin, Pierre-François
Guillon, Antoine
Pourcher, Valérie
Boutolleau, David
Vabret, Astrid
Burrel, Sonia
Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title_full Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title_fullStr Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title_full_unstemmed Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title_short Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France
title_sort fatal measles inclusion-body encephalitis in adult with untreated aids, france
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454109/
https://www.ncbi.nlm.nih.gov/pubmed/32818389
http://dx.doi.org/10.3201/eid2609.200366
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