Rapid exploration of the epitope coverage produced by an Ebola survivor to guide the discovery of therapeutic antibody cocktails

BACKGROUND: Development of successful neutralizing antibodies is dependent upon broad epitope coverage to increase the likelihood of achieving therapeutic function. Recent advances in synthetic biology have allowed us to conduct an epitope binning study on a large panel of antibodies identified to b...

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Detalles Bibliográficos
Autores principales: Yuan, Tom Z, Lujan Hernandez, Ana G, Keane, Erica, Liu, Qiang, Axelrod, Fumiko, Kailasan, Shweta, Noonan-Shueh, Madeleine, Aman, Mohammad Javad, Sato, Aaron K, Abdiche, Yasmina N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454256/
https://www.ncbi.nlm.nih.gov/pubmed/33912793
http://dx.doi.org/10.1093/abt/tbaa016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454256/
https://www.ncbi.nlm.nih.gov/pubmed/33912793
http://dx.doi.org/10.1093/abt/tbaa016

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