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Rapid exploration of the epitope coverage produced by an Ebola survivor to guide the discovery of therapeutic antibody cocktails
BACKGROUND: Development of successful neutralizing antibodies is dependent upon broad epitope coverage to increase the likelihood of achieving therapeutic function. Recent advances in synthetic biology have allowed us to conduct an epitope binning study on a large panel of antibodies identified to b...
Autores principales: | Yuan, Tom Z, Lujan Hernandez, Ana G, Keane, Erica, Liu, Qiang, Axelrod, Fumiko, Kailasan, Shweta, Noonan-Shueh, Madeleine, Aman, Mohammad Javad, Sato, Aaron K, Abdiche, Yasmina N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454256/ https://www.ncbi.nlm.nih.gov/pubmed/33912793 http://dx.doi.org/10.1093/abt/tbaa016 |
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