Cargando…

Plasma From Recovered COVID-19 Patients Inhibits Spike Protein Binding to ACE2 in a Microsphere-Based Inhibition Assay

We present a microsphere-based flow cytometry assay that quantifies the ability of plasma to inhibit the binding of spike protein to angiotensin-converting enzyme 2. Plasma from 22 patients who had recovered from mild coronavirus disease 2019 (COVID-19) and expressed anti–spike protein trimer immuno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gniffke, Edward P, Harrington, Whitney E, Dambrauskas, Nicholas, Jiang, Yonghou, Trakhimets, Olesya, Vigdorovich, Vladimir, Frenkel, Lisa, Sather, D Noah, Smith, Stephen E P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454725/ https://www.ncbi.nlm.nih.gov/pubmed/32798222 http://dx.doi.org/10.1093/infdis/jiaa508

Ejemplares similares

Rapid decline of neutralizing antibodies is associated with decay of IgM in adults recovered from mild COVID-19
por: Harrington, Whitney E., et al.
Publicado: (2021)

A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2
por: Tsegay, Kaleb B., et al.
Publicado: (2021)

Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates
por: Fisher, Bridget S., et al.
Publicado: (2020)

Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies
por: Wilder, Brandon K., et al.
Publicado: (2022)

Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection
por: Visweswaran, Ganesh Ram R., et al.
Publicado: (2022)

Persistent Nonviral Plasmid Vector in Nasal Tissues Causes False-Positive SARS-CoV-2 Diagnostic Nucleic Acid Tests
por: Beck, Ingrid A., et al.
Publicado: (2022)

Repertoire comparison of the B-cell receptor-encoding loci in humans and rhesus macaques by next-generation sequencing
por: Vigdorovich, Vladimir, et al.
Publicado: (2016)

Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus
por: Amanat, Fatima, et al.
Publicado: (2021)

Persistent Symptoms in Patients Recovering From COVID-19 in Denmark
por: Leth, Steffen, et al.
Publicado: (2021)

Persistent Symptoms and Association With Inflammatory Cytokine Signatures in Recovered Coronavirus Disease 2019 Patients
por: Ong, Sean Wei Xiang, et al.
Publicado: (2021)

ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19
por: Pinto, Bruna G G, et al.
Publicado: (2020)

A Multiplex Microsphere IgG Assay for SARS-CoV-2 Using ACE2-Mediated Inhibition as a Surrogate for Neutralization
por: Cameron, Andrew, et al.
Publicado: (2021)

Retinal and peripapillary vessel density increase in recovered COVID-19 children by optical coherence tomography angiography
por: Guemes-Villahoz, Noemi, et al.
Publicado: (2021)

A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection
por: Schäfer, Carola, et al.
Publicado: (2020)

Immunization Mandates, Vaccination Coverage, and Exemption Rates in the United States
por: Shaw, Jana, et al.
Publicado: (2018)

IgG Against Human Betacoronavirus Spike Proteins Correlates With SARS-CoV-2 Anti-Spike IgG Responses and COVID-19 Disease Severity
por: Wang, Jiong, et al.
Publicado: (2022)

Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination
por: Loeb, Nathalie, et al.
Publicado: (2020)

Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2
por: Zhang, Yongjing, et al.
Publicado: (2021)

Factor Xa Inhibition Reduces Coagulation Activity but Not Inflammation Among People With HIV: A Randomized Clinical Trial
por: Baker, Jason V, et al.
Publicado: (2020)

Characteristics of Salmonella Recovered From Stools of Children Enrolled in the Global Enteric Multicenter Study
por: Kasumba, Irene N, et al.
Publicado: (2021)

Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein
por: Sagar, Satish, et al.
Publicado: (2021)

Human Cytomegalovirus Infection of Epithelial Cells Increases SARS-CoV-2 Superinfection by Upregulating the ACE2 Receptor
por: Perera, Marianne R, et al.
Publicado: (2022)

Laser-facilitated epicutaneous immunization of mice with SARS-CoV-2 spike protein induces antibodies inhibiting spike/ACE2 binding
por: Scheiblhofer, Sandra, et al.
Publicado: (2021)

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages
por: Schafer, Carola, et al.
Publicado: (2018)

Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus
por: Wang, Nan, et al.
Publicado: (2020)

Proteinuria in systemic sclerosis: reversal by ACE inhibition
por: Schuster, J., et al.
Publicado: (2013)

Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction
por: Ahamad, Shahzaib, et al.
Publicado: (2022)

The spike-ACE2 interaction underlying SARS-CoV-2 infection and inhibition is enhanced by intermolecular cross linking
por: Asor, Roi, et al.
Publicado: (2022)

Synthetic carbohydrate-binding agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2
por: Francesconi, Oscar, et al.
Publicado: (2022)

Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay
por: Xiang, Yusen, et al.
Publicado: (2023)

Hemagglutination Inhibition Antibody Titers as a Correlate of Protection Against Seasonal A/H3N2 Influenza Disease
por: Benoit, Anne, et al.
Publicado: (2015)

Spike-specific T cells are enriched in breastmilk following SARS-CoV-2 mRNA vaccination
por: Armistead, Blair, et al.
Publicado: (2022)

Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies
por: Shaltiel-Karyo, Ronit, et al.
Publicado: (2010)

Commercial Immunoglobulin Products Contain Neutralizing Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein
por: Upasani, Vinit, et al.
Publicado: (2023)

Evaluation of a Cryptococcal Antigen Lateral Flow Assay and Cryptococcal Antigen Positivity at a Large Public Hospital in Atlanta, Georgia
por: Harrington, Kristin R V, et al.
Publicado: (2021)

Impact of Casirivimab-Imdevimab on Severe Acute Respiratory Syndrome Coronavirus 2 Delta Variant Nasopharyngeal Virus Load and Spike Quasispecies
por: Vellas, Camille, et al.
Publicado: (2022)

Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice
por: Tyrankiewicz, Urszula, et al.
Publicado: (2021)

Spike-specific T cells are enriched in breastmilk following SARS-CoV-2 mRNA vaccination
por: Armistead, Blair, et al.
Publicado: (2023)

Spike residue 403 affects binding of coronavirus spikes to human ACE2
por: Zech, Fabian, et al.
Publicado: (2021)

ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin
por: Partridge, Lynda J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_upo2mau604o1ac6mqeo6pp9uhe