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Intra-genome variability in the dinucleotide composition of SARS-CoV-2

CpG dinucleotides are under-represented in the genomes of single-stranded RNA viruses, and SARS-CoV-2 is no exception to this. Artificial modification of CpG frequency is a valid approach for live attenuated vaccine development; if this is to be applied to SARS-CoV-2, we must first understand the ro...

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Detalles Bibliográficos
Autores principales:	Digard, Paul, Lee, Hui Min, Sharp, Colin, Grey, Finn, Gaunt, Eleanor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454914/ https://www.ncbi.nlm.nih.gov/pubmed/33029383 http://dx.doi.org/10.1093/ve/veaa057

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