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Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA
The kinetochore, a multi-protein complex assembled on centromeres, is essential to segregate chromosomes during cell division. Deficiencies in kinetochore function can lead to chromosomal instability and aneuploidy—a hallmark of cancer cells. Kinetochore function is controlled by recruitment of regu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455000/ https://www.ncbi.nlm.nih.gov/pubmed/32810142 http://dx.doi.org/10.1371/journal.pgen.1008990 |