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City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455036/ https://www.ncbi.nlm.nih.gov/pubmed/32857824 http://dx.doi.org/10.1371/journal.pone.0238411 |
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author | Peng, Tailai Liu, Xinhao Ni, Hefeng Cui, Zhe Du, Lei |
author_facet | Peng, Tailai Liu, Xinhao Ni, Hefeng Cui, Zhe Du, Lei |
author_sort | Peng, Tailai |
collection | PubMed |
description | BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16. METHOD: To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point. RESULTS: The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan. CONCLUSION: City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic. |
format | Online Article Text |
id | pubmed-7455036 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-74550362020-09-02 City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model Peng, Tailai Liu, Xinhao Ni, Hefeng Cui, Zhe Du, Lei PLoS One Research Article BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16. METHOD: To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point. RESULTS: The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan. CONCLUSION: City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic. Public Library of Science 2020-08-28 /pmc/articles/PMC7455036/ /pubmed/32857824 http://dx.doi.org/10.1371/journal.pone.0238411 Text en © 2020 Peng et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Peng, Tailai Liu, Xinhao Ni, Hefeng Cui, Zhe Du, Lei City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title | City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title_full | City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title_fullStr | City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title_full_unstemmed | City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title_short | City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model |
title_sort | city lockdown and nationwide intensive community screening are effective in controlling the covid-19 epidemic: analysis based on a modified sir model |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455036/ https://www.ncbi.nlm.nih.gov/pubmed/32857824 http://dx.doi.org/10.1371/journal.pone.0238411 |
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