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City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model

BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community s...

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Autores principales: Peng, Tailai, Liu, Xinhao, Ni, Hefeng, Cui, Zhe, Du, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455036/
https://www.ncbi.nlm.nih.gov/pubmed/32857824
http://dx.doi.org/10.1371/journal.pone.0238411
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author Peng, Tailai
Liu, Xinhao
Ni, Hefeng
Cui, Zhe
Du, Lei
author_facet Peng, Tailai
Liu, Xinhao
Ni, Hefeng
Cui, Zhe
Du, Lei
author_sort Peng, Tailai
collection PubMed
description BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16. METHOD: To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point. RESULTS: The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan. CONCLUSION: City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic.
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spelling pubmed-74550362020-09-02 City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model Peng, Tailai Liu, Xinhao Ni, Hefeng Cui, Zhe Du, Lei PLoS One Research Article BACKGROUND: In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16. METHOD: To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point. RESULTS: The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan. CONCLUSION: City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic. Public Library of Science 2020-08-28 /pmc/articles/PMC7455036/ /pubmed/32857824 http://dx.doi.org/10.1371/journal.pone.0238411 Text en © 2020 Peng et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Peng, Tailai
Liu, Xinhao
Ni, Hefeng
Cui, Zhe
Du, Lei
City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title_full City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title_fullStr City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title_full_unstemmed City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title_short City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic: Analysis based on a modified SIR model
title_sort city lockdown and nationwide intensive community screening are effective in controlling the covid-19 epidemic: analysis based on a modified sir model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455036/
https://www.ncbi.nlm.nih.gov/pubmed/32857824
http://dx.doi.org/10.1371/journal.pone.0238411
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