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Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well understood. We hypothesized that ancestry would significantly influence gene express...

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Detalles Bibliográficos
Autores principales:	Catalina, Michelle D., Bachali, Prathyusha, Yeo, Anthony E., Geraci, Nicholas S., Petri, Michelle A., Grammer, Amrie C., Lipsky, Peter E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455079/ https://www.ncbi.nlm.nih.gov/pubmed/32759501 http://dx.doi.org/10.1172/jci.insight.140380

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