Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

BACKGROUND: Genomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in patients, we tested whether left atrial PITX2 affects recurrent AF after AF ablation. METHODS: mRNA concentrations of PITX2 and its cardiac...

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Detalles Bibliográficos
Autores principales: Reyat, Jasmeet S., Chua, Winnie, Cardoso, Victor R., Witten, Anika, Kastner, Peter M., Kabir, S. Nashitha, Sinner, Moritz F., Wesselink, Robin, Holmes, Andrew P., Pavlovic, Davor, Stoll, Monika, Kääb, Stefan, Gkoutos, Georgios V., de Groot, Joris R., Kirchhof, Paulus, Fabritz, Larissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455124/
https://www.ncbi.nlm.nih.gov/pubmed/32814717
http://dx.doi.org/10.1172/jci.insight.139179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455124/
https://www.ncbi.nlm.nih.gov/pubmed/32814717
http://dx.doi.org/10.1172/jci.insight.139179

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