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Human C. difficile toxin–specific memory B cell repertoires encode poorly neutralizing antibodies

Clostridioides difficile is a leading cause of nosocomial infection responsible for significant morbidity and mortality with limited options for therapy. Secreted C. difficile toxin B (TcdB) is a major contributor to disease pathology, and select TcdB-specific Abs may protect against disease recurre...

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Detalles Bibliográficos
Autores principales:	Shah, Hemangi B., Smith, Kenneth, Scott, Edgar J., Larabee, Jason L., James, Judith A., Ballard, Jimmy D., Lang, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455132/ https://www.ncbi.nlm.nih.gov/pubmed/32663199 http://dx.doi.org/10.1172/jci.insight.138137

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