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Risk-associated alterations in marrow T cells in pediatric leukemia
Current management of childhood leukemia is tailored based on disease risk determined by clinical features at presentation. Whether properties of the host immune response impact disease risk and outcome is not known. Here, we combine mass cytometry, single cell genomics, and functional studies to ch...
Autores principales: | Bailur, Jithendra Kini, McCachren, Samuel S., Pendleton, Katherine, Vasquez, Juan C., Lim, Hong Seo, Duffy, Alyssa, Doxie, Deon B., Kaushal, Akhilesh, Foster, Connor, DeRyckere, Deborah, Castellino, Sharon, Kemp, Melissa L., Qiu, Peng, Dhodapkar, Madhav V., Dhodapkar, Kavita M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455136/ https://www.ncbi.nlm.nih.gov/pubmed/32692727 http://dx.doi.org/10.1172/jci.insight.140179 |
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