Fluid-electrolyte homeostasis requires histone deacetylase function

Histone deacetylase (HDAC) enzymes regulate transcription through epigenetic modification of chromatin structure, but their specific functions in the kidney remain elusive. We discovered that the human kidney expresses class I HDACs. Kidney medulla-specific inhibition of class I HDACs in the rat dur...

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Detalles Bibliográficos
Autores principales: Hyndman, Kelly A., Speed, Joshua S., Mendoza, Luciano D., Allan, John M., Colson, Jackson, Sedaka, Randee, Jin, Chunhua, Jung, Hyun Jun, El-Dahr, Samir, Pollock, David M., Pollock, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455138/
https://www.ncbi.nlm.nih.gov/pubmed/32673289
http://dx.doi.org/10.1172/jci.insight.137792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455138/
https://www.ncbi.nlm.nih.gov/pubmed/32673289
http://dx.doi.org/10.1172/jci.insight.137792

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