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The NEMP family supports metazoan fertility and nuclear envelope stiffness

Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause; however, it is unclear whether NEMP1 has any role in fertility. We show that whole-animal loss of NEMP1 homologs in Drosophila, Caenorhabditis...

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Detalles Bibliográficos
Autores principales: Tsatskis, Yonit, Rosenfeld, Robyn, Pearson, Joel D., Boswell, Curtis, Qu, Yi, Kim, Kyunga, Fabian, Lacramioara, Mohammad, Ariz, Wang, Xian, Robson, Michael I., Krchma, Karen, Wu, Jun, Gonçalves, João, Hodzic, Didier, Wu, Shu, Potter, Daniel, Pelletier, Laurence, Dunham, Wade H., Gingras, Anne-Claude, Sun, Yu, Meng, Jin, Godt, Dorothea, Schedl, Tim, Ciruna, Brian, Choi, Kyunghee, Perry, John R. B., Bremner, Rod, Schirmer, Eric C., Brill, Julie A., Jurisicova, Andrea, McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455189/
https://www.ncbi.nlm.nih.gov/pubmed/32923640
http://dx.doi.org/10.1126/sciadv.abb4591

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