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Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic disease caused by a disordered immune system. We present a case of reactive HLH (RHLH) with uncommon skin findings in a 35-year-old African American female with a history of hidradenitis suppurativa and morbid obesity. Skin findings on p...

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Detalles Bibliográficos
Autores principales: Dourra, Mohsen, Mussad, Shiab, Singer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455388/
https://www.ncbi.nlm.nih.gov/pubmed/32874817
http://dx.doi.org/10.7759/cureus.10089
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author Dourra, Mohsen
Mussad, Shiab
Singer, Robert
author_facet Dourra, Mohsen
Mussad, Shiab
Singer, Robert
author_sort Dourra, Mohsen
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic disease caused by a disordered immune system. We present a case of reactive HLH (RHLH) with uncommon skin findings in a 35-year-old African American female with a history of hidradenitis suppurativa and morbid obesity. Skin findings on physical exam revealed bullous, ecchymotic, hypopigmented, and ulcerated lesions. The literature on the cutaneous lesions of RHLH is limited. Skin findings are an underrecognized feature of RHLH and can help alert to its presence or its recurrence after treatment.
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spelling pubmed-74553882020-08-31 Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis Dourra, Mohsen Mussad, Shiab Singer, Robert Cureus Dermatology Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic disease caused by a disordered immune system. We present a case of reactive HLH (RHLH) with uncommon skin findings in a 35-year-old African American female with a history of hidradenitis suppurativa and morbid obesity. Skin findings on physical exam revealed bullous, ecchymotic, hypopigmented, and ulcerated lesions. The literature on the cutaneous lesions of RHLH is limited. Skin findings are an underrecognized feature of RHLH and can help alert to its presence or its recurrence after treatment. Cureus 2020-08-27 /pmc/articles/PMC7455388/ /pubmed/32874817 http://dx.doi.org/10.7759/cureus.10089 Text en Copyright © 2020, Dourra et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Dourra, Mohsen
Mussad, Shiab
Singer, Robert
Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title_full Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title_fullStr Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title_full_unstemmed Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title_short Cutaneous Manifestations in a Patient With Reactive Hemophagocytic Lymphohistiocytosis
title_sort cutaneous manifestations in a patient with reactive hemophagocytic lymphohistiocytosis
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455388/
https://www.ncbi.nlm.nih.gov/pubmed/32874817
http://dx.doi.org/10.7759/cureus.10089
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