Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1

RNA 3′ end processing provides a source of transcriptome diversification which affects various (patho)-physiological processes. A prime example is the transcript isoform switch that leads to the read-through expression of the long non-coding RNA NEAT1_2, at the expense of the shorter polyadenylated...

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Detalles Bibliográficos
Autores principales: Barra, Jasmine, Gaidosh, Gabriel S., Blumenthal, Ezra, Beckedorff, Felipe, Tayari, Mina M., Kirstein, Nina, Karakach, Tobias K., Jensen, Torben Heick, Impens, Francis, Gevaert, Kris, Leucci, Eleonora, Shiekhattar, Ramin, Marine, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455494/
https://www.ncbi.nlm.nih.gov/pubmed/32923585
http://dx.doi.org/10.1126/sciadv.aaz9072

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