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Chromosome drives via CRISPR-Cas9 in yeast
Self-propagating drive systems are capable of causing non-Mendelian inheritance. Here, we report a drive system in yeast referred to as a chromosome drive that eliminates the target chromosome via CRISPR-Cas9, enabling the transmission of the desired chromosome. Our results show that the entire Sacc...
Autores principales: | Xu, Hui, Han, Mingzhe, Zhou, Shiyi, Li, Bing-Zhi, Wu, Yi, Yuan, Ying-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455567/ https://www.ncbi.nlm.nih.gov/pubmed/32859906 http://dx.doi.org/10.1038/s41467-020-18222-0 |
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