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Wnt activation as a therapeutic strategy in medulloblastoma
Medulloblastoma (MB) is defined by four molecular subgroups (Wnt, Shh, Group 3, Group 4) with Wnt MB having the most favorable prognosis. Since prior reports have illustrated the antitumorigenic role of Wnt activation in Shh MB, we aimed to assess the effects of activated canonical Wnt signaling in...
Autores principales: | Manoranjan, Branavan, Venugopal, Chitra, Bakhshinyan, David, Adile, Ashley A., Richards, Laura, Kameda-Smith, Michelle M., Whitley, Owen, Dvorkin-Gheva, Anna, Subapanditha, Minomi, Savage, Neil, Tatari, Nazanin, McKenna, Dillon, Bassey-Archibong, Blessing, Winegarden, Neil, Hallett, Robin, Provias, John P., Yarascavitch, Blake, Ajani, Olufemi, Fleming, Adam, Bader, Gary D., Pugh, Trevor J., Doble, Bradley W., Singh, Sheila K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455709/ https://www.ncbi.nlm.nih.gov/pubmed/32859895 http://dx.doi.org/10.1038/s41467-020-17953-4 |
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