Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity

Immune-therapy is an attractive alternative therapeutic approach for targeting central nervous system (CNS) tumors and the constituency of the Tumor Immune Microenvironment (TIME) likely to predict patient response. Here, we describe the TIME of >6000 primarily pediatric CNS tumors using a deconv...

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Detalles Bibliográficos
Autores principales: Grabovska, Yura, Mackay, Alan, O’Hare, Patricia, Crosier, Stephen, Finetti, Martina, Schwalbe, Edward C., Pickles, Jessica C., Fairchild, Amy R., Avery, Aimee, Cockle, Julia, Hill, Rebecca, Lindsey, Janet, Hicks, Debbie, Kristiansen, Mark, Chalker, Jane, Anderson, John, Hargrave, Darren, Jacques, Thomas S., Straathof, Karin, Bailey, Simon, Jones, Chris, Clifford, Steven C., Williamson, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455736/
https://www.ncbi.nlm.nih.gov/pubmed/32859926
http://dx.doi.org/10.1038/s41467-020-18070-y

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