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Uterine Carcinosarcoma: A Case Report and Literature Review

Uterine carcinosarcomas are rare and extremely aggressive undifferentiated carcinomas which include both carcinomatous and sarcomatous elements. A 52-year-old female presented with heavy irregular menstrual bleeding for several years and new right elbow pain and swelling. Ultrasound and computed tom...

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Autores principales: Kord, Ali, Rabiee, Behnam, Elbaz Younes, Ismail, Xie, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455848/
https://www.ncbi.nlm.nih.gov/pubmed/32884852
http://dx.doi.org/10.1155/2020/8816348
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author Kord, Ali
Rabiee, Behnam
Elbaz Younes, Ismail
Xie, Karen L.
author_facet Kord, Ali
Rabiee, Behnam
Elbaz Younes, Ismail
Xie, Karen L.
author_sort Kord, Ali
collection PubMed
description Uterine carcinosarcomas are rare and extremely aggressive undifferentiated carcinomas which include both carcinomatous and sarcomatous elements. A 52-year-old female presented with heavy irregular menstrual bleeding for several years and new right elbow pain and swelling. Ultrasound and computed tomography showed a large uterine mass with regional and distant metastatic lymphadenopathy and suspicious findings of osseous metastasis to the right elbow. A biopsy confirmed uterine carcinosarcoma, and the patient underwent chemotherapy and then surgical resection of the uterine mass with palliative radiotherapy of the right elbow. The postoperative imaging showed new metastasis, and the patient was scheduled to start on immunotherapy. Considering the highly invasive nature of uterine carcinosarcomas, timely detection of this cancer using characteristic imaging and pathology findings is of extreme importance to improve the patient's survival.
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spelling pubmed-74558482020-09-02 Uterine Carcinosarcoma: A Case Report and Literature Review Kord, Ali Rabiee, Behnam Elbaz Younes, Ismail Xie, Karen L. Case Rep Obstet Gynecol Case Report Uterine carcinosarcomas are rare and extremely aggressive undifferentiated carcinomas which include both carcinomatous and sarcomatous elements. A 52-year-old female presented with heavy irregular menstrual bleeding for several years and new right elbow pain and swelling. Ultrasound and computed tomography showed a large uterine mass with regional and distant metastatic lymphadenopathy and suspicious findings of osseous metastasis to the right elbow. A biopsy confirmed uterine carcinosarcoma, and the patient underwent chemotherapy and then surgical resection of the uterine mass with palliative radiotherapy of the right elbow. The postoperative imaging showed new metastasis, and the patient was scheduled to start on immunotherapy. Considering the highly invasive nature of uterine carcinosarcomas, timely detection of this cancer using characteristic imaging and pathology findings is of extreme importance to improve the patient's survival. Hindawi 2020-08-20 /pmc/articles/PMC7455848/ /pubmed/32884852 http://dx.doi.org/10.1155/2020/8816348 Text en Copyright © 2020 Ali Kord et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kord, Ali
Rabiee, Behnam
Elbaz Younes, Ismail
Xie, Karen L.
Uterine Carcinosarcoma: A Case Report and Literature Review
title Uterine Carcinosarcoma: A Case Report and Literature Review
title_full Uterine Carcinosarcoma: A Case Report and Literature Review
title_fullStr Uterine Carcinosarcoma: A Case Report and Literature Review
title_full_unstemmed Uterine Carcinosarcoma: A Case Report and Literature Review
title_short Uterine Carcinosarcoma: A Case Report and Literature Review
title_sort uterine carcinosarcoma: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455848/
https://www.ncbi.nlm.nih.gov/pubmed/32884852
http://dx.doi.org/10.1155/2020/8816348
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